E2F1-MEDIATED INDUCTION OF NFYB ATTENUATES APOPTOSIS VIA JOINT REGULATION OF A PRO-SURVIVAL TRANSCRIPTIONAL PROGRAM.

E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program.

The E2F1 transcription factor regulates cell proliferation and apoptosis through the control of a considerable variety of target genes.Previous work has detailed the role of other transcription factors in mediating the Battery specificity of E2F function.Here we identify the NF-YB transcription factor as a novel direct E2F1 target.Genome-wide expre

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On the Generalizability of Machine Learning Classification Algorithms and Their Application to the Framingham Heart Study

The use of machine learning algorithms in healthcare can amplify social injustices and health inequities.While the exacerbation of biases can occur and be compounded during problem selection, data collection, and outcome definition, this research pertains to the generalizability impediments that occur during the development and post-deployment of m

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WAR CRIMES IN GAZA STRIP FROM YEAR 2008 2021: INDIVIDUAL CRIMINAL RESPONSIBILITY UNDER THE LEGAL FRAMEWORK OF ROME STATUTE OF THE INTERNATIONAL CRIMINAL COURT

From the end of the year 2008 to 2021, Israel committed four wars in the Gaza Strip.These wars were known as Operation Cast Lead in 2009, Operation Pillar of Cloud in 2012, Operation Protective Edge in 2014, and Operation Guardian of the Walls in 2021.The destructive impacts on vital facilities in Gaza, including schools, universities, mosques, hos

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